Changing the body’s thermostat: From Brain Circuits to Clinical Target

MCTN | IZN Lecture: "Changing the body’s thermostat: From Brain Circuits to Clinical Target", Prof. Natalia Machado, Beth Israel Deaconess Medical Center (BIDMC) & Harvard Medical School, Boston, USA

Natalia Machado is a neuroscientist and Assistant Professor of Neurology at Beth Israel Deaconess Medical Center (BIDMC) and Harvard Medical School. Her research investigates how the brain regulates body temperature, metabolism, and physiological responses to stress, with a particular focus on the mechanisms underlying fever and competing metabolic demands.

Her work also explores how modulating body temperature and metabolism can protect the brain and other vital organs from ischemic injury. Her laboratory is developing innovative approaches to therapeutic hypothermia, with the goal of reducing tissue damage after stroke and cardiac arrest and exploring its potential applications in other diseases.

Natalia Machado’s research has advanced the understanding of the interactions between the brain, metabolism, and systemic physiology, with promising implications for patients affected by stroke, inflammatory conditions, and metabolic disorders.

Language: English

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